| pharmacologist30 |
 Wysłany: Śro 20:36, 15 Lis 2006 Temat postu: Hydrocodone Drug Resources Online |
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Hydrocodone is an effective antitussive (anti-cough) agent, and as an opiate
it is also an effective analgesic for mild to moderate pain control. Five mg
of hydrocodone is equivalent to 30 mg of codeine when administered orally.
Early comparisons concluded that hydrocodone and morphine were equipotent
for pain control in humans. However, it is now considered that a dose of 15
mg (1/4 gr) of hydrocodone is equivalent to 10 mg (1/6 gr) of morphine.
Hydrocodone is considered to be morphine-like in all respects.
There are over 200 products containing hydrocodone in the U.S. In its most
usual product forms hydrocodone is combined with acetaminophen (Vicodin,
Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen
(Vicoprofen), and antihistamines (Hycomine). Both tablet and liquid forms of
hydrocodone are available (e.g., Tussionex)
Hydrocodone is in Schedule II of the Controlled Substances Act. Preparations
containing hydrocodone in combination with other non-narcotic medicinal
ingredients are in Schedule III.
Vicodin, hydrocodone in combination with acetaminophen, is a commonly abused
version of hydrocodone. Vicodin, as with all narcotic analgesics, can be
habit forming---causing dependence, tolerance, and withdrawal symptoms if
not used as it is prescribed. Even when used as prescribed, the following
effects are possible:
COMMON SIDE EFFECTS MAY INCLUDE: dizziness, light-headedness, nausea,
sedation, vomiting, and constipation.
LESS COMMON SIDE EFFECTS: allergic reactions, blood disorders, mood changes,
mental cloudiness, anxiety, lethargy, urine retention, ureteral spasm,
irregular breathing, respiratory depression, and skin rash.
SYMPTOMS OF OVERDOSE: bluish tinge to skin, cold and clammy skin, extreme
sleepiness progressing to a possible state of unresponsiveness or coma,
heart problems, heavy perspiration, kidney problems, limp muscles, liver
failure, low blood pressure, nausea, slow heartbeat, troubled or slowed
breathing, and vomiting.
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